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Analysis of the intrinsically disordered N-terminal fragment of human glucocorticoid receptor fragments revealed that it is characterized by the max of 340 nm, suggesting an external location of Trp residues, whereas trimethylamine N-oxide-induced folding of this fragment resulted in a blue shift of fluorescence maximum by more than 10 nm ( In 1971, Paul R

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Very large doses can result in lactic acidosis (a drop in pH of the blood) and coma (Ferner 2011

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Apesar desses resultados, a endocrinologista Cristina Schreiber ressalta que os estudos disponveis no autorizam extrapolar os efeitos observados para o uso oral ou injetvel do composto