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We hypothesize that SAC inhibits the E3 ubiquitin ligase activity of KEAP1 through interaction, thereby blocking the ubiquitination-mediated degradation of NRF2, stabilizing the NRF2 protein, and activating the transcription of various protective genes, including antioxidant enzymes

295 Claussnitzer, M

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Targets skin laxity, horizontal lines, crepey texture, and loss of jawline definition while improving elasticity, collagen remodeling, firmness, and contour

Function: It increases GH and insulin-like growth factor 1 (IGF-1) production without raising prolactin levels significantly