The tissue clearing CLARITY protocol was used to visualize epitope distribution in whole animals for acetaminophen immunofluorescence
Zhu J, Wang Z, Tao L, Han L, Huang Q, Fang X, Yang K, Huang G, Zheng Z, Yawalkar N, Zhang Z, Yan K (2022) MTHFR Gene Polymorphism Association with psoriatic arthritis risk and the efficacy and hepatotoxicity of methotrexate in psoriasis
10.1016/j.redox.2013.05.003 Redox Biol
Frequency varies based on your goals
Your body produces it naturally, and its present in virtually every cell, as written in WebMD article Glutathione: What you should know
Ferroptotic macrophages can trigger a systemic inflammatory response by releasing DAMPs and pro-inflammatory cytokines that can activate the inflammasome