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Participants were randomly assigned (1:1:1:1:1:1:1:1:1 ratio) to one of the nine treatment groups using a centralized interactive web randomization system

228 Superoxide radicals that are formed are converted to hydrogen peroxide by the action of the copper-containing enzyme superoxide dismutase (SOD)

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Patients should be counselled on strategies to minimise gastrointestinal symptoms, such as eating smaller meals, avoiding high-fat foods, and staying well-hydrated