Al-Karadsheh, T
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IGF-1 LR3 retains the ability to bind IGF-1 and insulin receptors but has reduced binding affinity to insulin-like growth factor-binding proteins (IGFBPs)
These drugs stimulate insulin release, suppress glucagon, slow the rate of gastric emptying, and enhance feelings of fullness (Cleveland Clinic 2024)
Options may include SGLT2 inhibitors, metformin, thiazolidinediones, or insulin for diabetes, noting that DPP-4 inhibitors also carry pancreatitis warnings
2014;29C:23-28