Methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy
People taking other medications, such as corticosteroids and psychotropic drugs (such as antidepressants) which can cause weight gain, may also find GLP-1 drugs dont work very well for them
The reason for this could be their nutritional status
Even the cooking method should be considered, since it may impact on the amount of goitrogen compounds released [160]
doi: 10.1186/s13223-020-00494-2 [PubMed] 33444815 Casimir-Brown RS, Kennard L, Kayode OS, Siew LQC, Makris M, Tsilochristou O, Chytiroglou E, Nakonechna A, Rutkowski K, Mirakian R, Wagner A
We get this question a lot