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Studies consistently demonstrate that weight lossthe primary effect of GLP-1 therapyimproves fertility outcomes by reducing insulin resistance, lowering inflammation, and restoring regular ovulation in people with obesity-related infertility

Corydalis saxicola Bunting total alkaloids improve NAFLD by suppressing de novo lipogenesis through the AMPK-SREBP1 axis

These doses are both approximately 4-times the maximum recommended human dose of 2,000 mg based on body surface area comparisons

Studies show that when the medication is stopped, people often regain weight, indicating that ongoing therapy might be needed to keep weight off [intermountainhealthcare.org]

It also warns that withholding therapy may not be risk-free and could raise concerns about hyperglycemia, cost, access, bias, and inequitable care

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