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Compiled from clinical pathology references

For patients experiencing persistent issues, temporary treatment interruption may be necessary while electrolytes are corrected and hydration restored, followed by reinitiation at a lower dose with more gradual titration

The tissue samples were lysed in 1 lysis buffer (20 mM Tris-HCL [pH 7.5], 150 mM NaCl, 1 mM Na2EDTA, 1 mM EGTA, 1% Triton X-100, 2.5 mM sodium pyrophosphate, 1 mM b-glycerophosphate, 1 mM Na3VO4, 1 mg/mL leupeptin) obtained from Cell Signaling Technology, supplemented with protease inhibitor 1 mM PMSF [29]

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