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Stopping abruptly can cause blood sugar fluctuations and weight regain

This can lead to: Recurrent gastrointestinal symptoms : Nausea, vomiting, diarrhoea, and constipation may return or worsen with each restart Injection site reactions : Redness, itching, or discomfort at the injection site Hypoglycaemia risk : Particularly relevant for patients taking Wegovy alongside other glucose-lowering medications Rare but serious adverse effects associated with semaglutide include acute pancreatitis (severe abdominal pain, nausea, vomiting), gallbladder disease, and potential thyroid effects

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Receptor Binding: MT1 predominantly targets MC1R, which plays a role in melanin production