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Upregulation of the low density lipoprotein receptor at the bloodbrain barrier:Intercommunications between brain capillary endothelial cells and astrocytes

If proteins fail to fold properly at the ER, they are ubiquitinated by E3 ligases

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The most common side effects of Ozempic include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, abdominal pain, and constipation, particularly during dose escalation

Key monitoring parameters include fasting and random blood glucose, HbA1c every 3 months, weight and waist circumference, blood pressure, and symptom assessment for nausea, dizziness, or hypoglycemia