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However, our negative results suggested the simply combination might not achieve an effect of 1 + 1 = 2

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Retatrutide represents the third generation of this research progression, adding glucagon receptor activation to the dual-agonist framework

doi: 10.1158/2326-6066.CIR-18-0507 233 MendlerANHuBPrinzPUKreutzMGottfriedENoessnerE