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Seiwerth and colleagues (Inflammopharmacology, 1999) documented effects on angiogenic growth factor pathway signalling, and subsequent work has expanded characterisation to include VEGF receptor 2 upregulation, endothelial cell migration in capillary-formation assays, and improved healing in ischemia-reperfusion preparations

doi: 10.3389/fmed.2026.1698091 Received 03 September 2025 Revised 16 March 2026 Accepted 19 March 2026 Published 20 April 2026 Volume 13 - 2026 Edited by Liliana Gabriela Popa, Carol Davila University of Medicine and Pharmacy, Romania Reviewed by Manoj B