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The trifluoromethyl group in the fluphenazine molecule turned out to be photolabile, which results in its hydrolysis and then substitution by a carboxylic group (in aqueous medium)
Heeren J, Scheja L
doi:10.3390/medicina59050985 Chandrakumar H, Khatun N, Gupta T, GrahamHill S, Zhyvotovska A, McFarlane SI
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This dual action synergistically enhances tumor cell death and improves the therapeutic index
Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer
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