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Preclinical research done in Toronto also showed that GLP-1 acted on the brain to reduce appetite, which helps with weight loss, and has been demonstrated to reduce the risk of heart attack and stroke

TB-500, in contrast, functions through actin sequestration, promoting cell migration and reducing inflammation via distinct cytokine pathways

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This reduces production of IL-1, IL-6, TNF-, and other cytokines driving chronic oral inflammation

Researchers believe this is due to increased ROS (increased oxidative stress) in the pancreatic beta cells.[ref] Related article : Type 2 Diabetes Genes Fatty liver disease: High homocysteine levels are associated with NAFLD (fatty liver disease, MAFLD)

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