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The carbons of citrate are used to transport mitochondrial acetyl-CoA to the cytosol where they can be used for the synthesis of fatty acids, cholesterol, and bile acids

This pathway aids in the production of GPX4, counteracting lipid peroxidation and deterring ferroptosis

Human brown adipocyte thermogenesis is driven by 2-AR stimulation

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Although the new FDA green light doesnt expand the number of people who may be eligible for the drug, since the sleep apnea approval is specifically for people with obesity, it could lead to insurance coverage for those with the condition on Medicare, which doesnt cover drugs solely for weight loss