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doi: 10.1016/j.cmet.2024.10.015 63 RhoHHayN

KLOW is not appropriate for patients who are pregnant or breastfeeding, have active cancer or a recent cancer history, or are on immunosuppressive therapy

Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats

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Moreover, use in vulnerable populations, including neonates and young children, requires careful riskbenefit evaluation to prevent GI complications and ensure safe administration (567)

This discovery formed the scientific basis for the development of AOD-9604 as a focused research tool for metabolic biology investigation